Producing cultivated meat requires isolating muscle stem cells — the building blocks of muscle tissue — from animal samples. But doing so at scale often depends on collagenase, an expensive enzyme used to break down tissue. Researchers at Chungbuk National University may have found a simpler, natural alternative that could make the process both cheaper and cleaner.

What the Patent RevealsThe newly published patent describes a method of isolating muscle satellite cells (the stem cells responsible for muscle growth) using natural proteases — enzymes found in fruits like kiwi, papaya, and pineapple. These fruit-derived enzymes gently separate the cells from the surrounding tissue, allowing them to be cultured and multiplied in a lab environment. The result: a lower-cost, food-safe, and readily available substitute for collagenase in cultivated meat production. (KR20250093169A)

The ApplicantChungbuk National University is a leading research institution in South Korea with a growing portfolio in food biotechnology and tissue engineering. This invention reflects its commitment to advancing sustainable food technologies that merge agricultural science with modern bioprocessing.

The InventorsCongratulations to Jungseok Choi, Solhee Lee, Sang-hun Park, Gyutae Park, Soyoung Jang and team for their contribution to the field.

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This post is based on publicly available information. Lab Grown Technologies is not affiliated with the inventors or organizations mentioned.

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