Heme Without Animals
The Mediterranean Food Lab’s fermentation breakthrough
There’s a very specific moment when you taste something and think, this isn’t just salty or savoury, it’s layered. Slightly metallic. Lingering in a way that feels familiar, even if you can’t quite place why. That’s the part of meat that’s been surprisingly hard to recreate, and it has less to do with texture than most people think.
Texture often gets most of the attention, but flavour is where many products still fall short. This patent points to a different approach. Instead of adding isolated compounds, it builds flavour from the ground up using fermentation and plant chemistry.

Turning plants into heme-like flavour
At the core of this invention (WO2026018239A1) is a fermentation process that combines plant materials rich in polyphenols or tannins with plant-derived metals such as iron, zinc, or copper. Through fermentation, these components form complexes that mimic the sensory profile associated with heme, the compound responsible for much of meat’s characteristic taste.
The result is a flavour material that delivers a mix of sweet, umami, metallic, bitter, and astringent notes in defined proportions. For example, the formulation specifies at least 55 percent sweet-associated compounds and a measurable metallic fraction, helping recreate that subtle iron-like edge people associate with cooked meat. The system also includes volatile compounds that contribute creamy, nutty, and earthy aromas.
What stands out is how this goes beyond simply adding iron. It uses fermentation to transform plant substrates like coffee, cacao, grapes, or even agricultural byproducts into something more complex and layered. The outcome is a clean-label, animal-free flavour system that can be added to broths, sauces, or meat alternatives to enhance depth and realism.
Building flavour from fermentation
The Mediterranean Food Lab has built its reputation around solid-state fermentation and ingredient transformation. Their work often focuses on turning overlooked plant materials into high-value flavour ingredients.
This patent fits neatly into that strategy. Rather than chasing one-to-one replacements for animal compounds, they are engineering flavour through interactions between naturally occurring plant molecules. It reflects a broader shift in food tech, where fermentation is used not just for preservation or protein production, but as a tool to design taste itself.
The Inventors
Congratulations and a warm thank you to the inventors: Ben Z. Goldberg, Barak Dror, Tom Levi, Asaf Gronovitch, Sivan Dor and Guy Harlev for advancing how we think about flavour in alternative proteins.
I’m Kandice Vincent, a writer and editor covering cellular agriculture, food tech, and the future of how we produce and consume food. I work closely with founders, researchers, and mission-driven companies to turn complex science into something people can actually understand. I care deeply about where food is headed, how we get there, and who’s shaping that future. Based in Mexico, I’m usually writing with my rescue dog Taco nearby, who remains unimpressed by patents but highly invested in mealtimes.
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This article is based on publicly available information. Lab Grown Technologies is not affiliated with the inventors or organizations mentioned.
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